Since then, I've been thinking a story about a woman who leaves Earth (and all her family and friends) at 22. Now she is 45 and realizing that over half her life has been spent in space, wondering if she has lost her humanity, and being put in situations to challenge her humanity.
So far I don't know much.... even her name, but I'm sure things will come to me. For example, I know that she'll have to face Earth. What I have to remember is to draw on my own feelings of loss and estrangement from my past.